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Plant

Grapefruit

Citrus × paradisi

Also known as: Citrus × paradisi

A large yellow-rind citrus fruit that arose in Barbados in the 17th or 18th century as a spontaneous hybrid between the sweet orange and the pomelo. The youngest of the major commercial citrus species — under three hundred years old, and the only one originating in the New World rather than Asia. The name 'grapefruit' refers to the fruit's habit of hanging in tight grape-like clusters on the branch. Mexico, China, Vietnam, the United States, and South Africa lead production; the fruit is also pharmacologically notable for interacting with a long list of medications via furanocoumarins that inhibit intestinal CYP3A4 enzymes.

Scientific

Citrus × paradisi is in family Rutaceae. A medium-sized evergreen tree reaching 5–6 m with glossy dark green leaves and white fragrant flowers. Fruits are 10–15 cm globes with a thick yellow or pink-blushed rind and segmented pulp ranging from pale yellow (white grapefruit) through pink to deep ruby red, depending on cultivar — the pigmentation is from carotenoids and lycopene rather than the anthocyanins that give blood oranges their color. Trees grow in clusters of 8–20 fruits hanging from short pedicels, giving the appearance of large yellow grapes on the branch and the source of the English common name.

The grapefruit is now understood to be an interspecific hybrid (Citrus maxima × Citrus sinensis) that arose spontaneously in Barbados in the 17th or 18th century, probably from pomelos brought to the Caribbean from East Asia growing alongside sweet oranges. The first documented description was by the Welsh naturalist Griffith Hughes in 1750.

Furanocoumarin drug interactions. Grapefruit pulp contains bergamottin and 6’,7’-dihydroxybergamottin — furanocoumarins that irreversibly inhibit intestinal CYP3A4, the enzyme that metabolizes many oral medications. A single grapefruit or 200 ml of juice can raise blood levels of a wide range of drugs (statins, calcium-channel blockers, immunosuppressants, some psychiatric drugs) for 24+ hours. Patients on these medications are routinely advised to avoid grapefruit entirely.

Cultural

Grapefruit cultivation expanded from Barbados across the Caribbean in the 18th century and reached Florida in the 1820s, where commercial production took off in the late 19th century and made grapefruit a familiar American breakfast fruit by the 1920s. The Ruby Red mutation appeared in a Texas orchard in 1929 and gave rise to most of the popular pink and red cultivars. The grapefruit-with-a-spoon-and-spiked-spoon breakfast and the grapefruit-half-with-broiled-sugar are mid-20th-century American conventions.

Global production

China leads global production by volume, followed by Vietnam, the United States, Mexico, and South Africa — though Asian production includes a large share of pomelos (Citrus maxima) statistically grouped with grapefruit in FAO data. Within the U.S., Texas (Rio Grande Valley) and Florida have historically been the major producers, with Florida’s industry severely affected by citrus greening disease in recent years.

See also

Auto-generated from this entry’s typed relations: frontmatter, grouped by relation type so the editorial signal isn’t flattened.

  • Shares approach with: [[orange]] · [[lemon]] · [[lime]]
  • Member of: [[plants]]

Sources

  • USDA Citrus Pathology — Citrus × paradisi
  • FAO commodity statistics
  • Wikipedia — Grapefruit

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